Garlic Parmesan Chicken Penne in Creamy Cajun Three-Cheese Sauce
A rich and creamy Garlic Parmesan Chicken Penne in Creamy Cajun Three-Cheese Sauce is a delightful dish that brings together the bold flavors of Cajun spices with the comforting essence of cheesy pasta. Perfect for weeknight dinners, this recipe is not only quick to prepare but also an impressive choice for gatherings. The unique blend of cheeses adds depth, while the chicken provides a hearty protein source, making it a satisfying meal for any occasion.
Why You’ll Love This Recipe
- Easy to Prepare: This dish comes together in just 30 minutes, making it ideal for busy weeknights.
- Flavorful Kick: The Cajun seasoning adds a delightful spice that elevates the overall taste of the pasta.
- Cheesy Goodness: With three types of cheese, every bite is packed with creaminess and flavor that cheese lovers will adore.
- Versatile Ingredients: You can easily adapt this recipe by adding your favorite vegetables or using different proteins.
- Family-Friendly: Kids and adults alike will enjoy this comforting meal, ensuring it’s a hit at the dinner table.
Tools and Preparation
To make this delicious Garlic Parmesan Chicken Penne in Creamy Cajun Three-Cheese Sauce, you’ll need a few essential tools to streamline your cooking process.
Essential Tools and Equipment
- Large skillet
- Pot for boiling pasta
- Cooking spoon
- Measuring cups and spoons
Importance of Each Tool
- Large skillet: This is crucial for cooking the chicken evenly and combining all ingredients seamlessly.
- Pot for boiling pasta: A good-sized pot ensures the penne cooks properly without sticking together.
- Cooking spoon: Helps to mix ingredients thoroughly and prevent burning during cooking.
- Measuring cups and spoons: Accurate measurements are key to achieving the perfect balance of flavors in your sauce.

Ingredients
A rich and creamy Garlic Parmesan Chicken Penne tossed in a flavorful Cajun three-cheese sauce. This comforting pasta dish is perfect for a quick weeknight dinner that’s packed with cheesy goodness and a spicy kick.
Ingredients:
– 1 lb boneless, skinless chicken breasts, cut into bite-sized pieces
– 1 tablespoon Cajun seasoning
– 12 oz penne pasta
– 2 tablespoons olive oil
– 3 tablespoons unsalted butter
– 4 cloves garlic, minced
– 1 ½ cups heavy cream
– ½ cup chicken broth
– ½ cup shredded mozzarella cheese
– ½ cup shredded cheddar cheese
– ½ cup grated Parmesan cheese
– Salt and freshly ground black pepper, to taste
– Fresh parsley, chopped (for garnish)
How to Make Garlic Parmesan Chicken Penne in Creamy Cajun Three-Cheese Sauce
Step 1: Cook the Penne Pasta
Cook penne pasta according to package instructions until al dente. Drain and set aside.
Step 2: Season the Chicken
Season chicken pieces with Cajun seasoning, salt, and pepper.
Step 3: Cook the Chicken
Heat olive oil in a large skillet over medium-high heat. Add chicken and cook until golden and cooked through, about 6–8 minutes. Remove chicken and set aside.
Step 4: Sauté Garlic
In the same skillet, melt butter over medium heat. Add garlic and sauté for 1–2 minutes until fragrant.
Step 5: Create the Sauce Base
Stir in heavy cream and chicken broth, bringing to a gentle simmer.
Step 6: Add Cheeses
Add mozzarella, cheddar, and Parmesan cheeses, stirring until melted and smooth.
Step 7: Combine Chicken with Sauce
Return chicken to the skillet and toss to coat with the sauce.
Step 8: Mix in Pasta
Add cooked penne pasta and toss until fully coated with the creamy cheese sauce.
Step 9: Garnish Before Serving
Garnish with fresh parsley before serving.
How to Serve Garlic Parmesan Chicken Penne in Creamy Cajun Three-Cheese Sauce
Serving Garlic Parmesan Chicken Penne in Creamy Cajun Three-Cheese Sauce is all about enhancing its rich flavors and creamy texture. Here are some delicious serving suggestions to elevate your dining experience.
Garnish with Fresh Herbs
- Chopped Parsley: A sprinkle of freshly chopped parsley adds a pop of color and freshness to balance the dish’s richness.
Pair with a Side Salad
- Caesar Salad: Crisp romaine lettuce topped with Caesar dressing, croutons, and shaved Parmesan complements the creamy pasta beautifully.
- Garden Salad: A mix of fresh greens, tomatoes, cucumbers, and a light vinaigrette provides a refreshing contrast.
Serve with Crusty Bread
- Garlic Bread: Warm, buttery garlic bread is perfect for soaking up the creamy sauce while adding an extra layer of flavor.
- French Baguette: Slices of crusty baguette can be served alongside for a delightful crunch.
Add a Protein Boost
- Grilled Shrimp: Topping your dish with grilled shrimp can add a seafood twist that pairs nicely with the Cajun flavors.
- Sliced Grilled Chicken: For extra protein, consider adding more chicken on top for a filling meal.
How to Perfect Garlic Parmesan Chicken Penne in Creamy Cajun Three-Cheese Sauce
Perfecting this dish ensures every bite brims with flavor and creaminess. Here are some tips to help you achieve that goal.
- Use Fresh Ingredients: Fresh garlic and high-quality cheeses make all the difference in flavor.
- Adjust Spice Levels: Tailor the amount of Cajun seasoning to your taste preference; start low if you’re sensitive to spice.
- Cook Pasta Al Dente: Ensure your pasta is cooked al dente so it maintains its texture when mixed with the sauce.
- Stir Constantly: When adding cheese, stir constantly over low heat to prevent it from clumping or burning.
- Let It Rest: Allow the dish to sit for a few minutes after cooking; this helps flavors meld together.
- Experiment with Cheeses: Feel free to mix different cheeses like gouda or pepper jack for added flavor complexity.
Best Side Dishes for Garlic Parmesan Chicken Penne in Creamy Cajun Three-Cheese Sauce
Complementing your Garlic Parmesan Chicken Penne in Creamy Cajun Three-Cheese Sauce with the right side dishes enhances the overall meal experience. Here are some excellent options:
- Garlic Mashed Potatoes — Creamy mashed potatoes infused with garlic provide comfort and pair well with the pasta’s richness.
- Steamed Broccoli — Lightly steamed broccoli adds color and nutrition without overshadowing the main dish.
- Roasted Vegetables — A medley of seasonal vegetables roasted until caramelized offers both flavor and texture contrast.
- Coleslaw — A crisp coleslaw adds crunch and tanginess, balancing the creaminess of the pasta.
- Corn on the Cob — Sweet corn on the cob brings sweetness that contrasts nicely with spicy Cajun flavors.
- Quinoa Salad — A light quinoa salad tossed with fresh veggies makes for a healthy and hearty side option.
Common Mistakes to Avoid
When making Garlic Parmesan Chicken Penne in Creamy Cajun Three-Cheese Sauce, it’s easy to run into a few common pitfalls. Here are some mistakes to watch out for.
- Bold seasoning: Over-seasoning can easily overpower the dish. Use the Cajun seasoning sparingly, and adjust it to your taste as you go.
- Bold cooking pasta: Cooking the penne pasta too long can lead to mushy noodles. Always follow package instructions and aim for al dente.
- Bold melting cheese: Adding cheese too quickly to the sauce can result in clumps. Gradually stir in the cheeses, allowing each to melt fully before adding more.
- Bold neglecting protein: Not checking that the chicken is fully cooked may ruin your dish. Ensure it’s golden brown and reaches an internal temperature of 165°F.
- Bold rushing preparation: Skipping prep work can lead to chaos in the kitchen. Chop garlic and measure all ingredients before starting to cook for a smoother process.

Storage & Reheating Instructions
Refrigerator Storage
- Store leftovers in an airtight container.
- Keep in the refrigerator for up to 3 days.
Freezing Garlic Parmesan Chicken Penne in Creamy Cajun Three-Cheese Sauce
- Allow the dish to cool completely before freezing.
- Use a freezer-safe container or bag; it will last up to 2 months.
Reheating Garlic Parmesan Chicken Penne in Creamy Cajun Three-Cheese Sauce
- Oven: Preheat to 350°F, place in a baking dish with a splash of cream or broth, cover, and heat until warmed through.
- Microwave: Place in a microwave-safe bowl, add a bit of cream or broth, cover loosely, and heat in intervals until hot.
- Stovetop: In a skillet over medium-low heat, add a splash of cream or broth and gently reheat while stirring.
Frequently Asked Questions
What makes Garlic Parmesan Chicken Penne in Creamy Cajun Three-Cheese Sauce unique?
This dish stands out due to its rich combination of flavors from three types of cheese mixed with spicy Cajun seasoning that adds a delightful kick.
Can I customize this recipe?
Absolutely! You can add vegetables like bell peppers or spinach for extra nutrition or swap out chicken for beef or turkey if desired.
How do I make this dish spicy?
To enhance the spice level, consider increasing the amount of Cajun seasoning or adding diced jalapeños for an extra kick.
Can I use other types of pasta?
Yes! While penne is great for holding sauce, you can use any pasta shape you prefer such as rotini, fusilli, or even spaghetti.
How long does this dish take to prepare?
The total time from start to finish is approximately 30 minutes, making it perfect for a quick weeknight dinner.
Final Thoughts
Garlic Parmesan Chicken Penne in Creamy Cajun Three-Cheese Sauce is not only comforting but also versatile. This creamy pasta dish is perfect for any occasion and can be customized with various proteins or veggies. Give it a try tonight!
Garlic Parmesan Chicken Penne in Creamy Cajun Three-Cheese Sauce
Indulge in a delightful bowl of Garlic Parmesan Chicken Penne in Creamy Cajun Three-Cheese Sauce, where comforting pasta meets a zesty kick. This rich and creamy dish features tender chicken coated in a decadent blend of mozzarella, cheddar, and Parmesan cheeses, all enhanced by the bold flavors of Cajun seasoning. Perfect for busy weeknights or special gatherings, this recipe is quick to prepare yet impressively satisfying. Each bite offers a harmonious blend of spice and creaminess that will leave everyone at the table asking for seconds.
- Prep Time: 10 minutes
- Cook Time: 20 minutes
- Total Time: 30 minutes
- Yield: Serves 4
- Category: Main
- Method: Stovetop
- Cuisine: American
Ingredients
- 1 lb boneless, skinless chicken breasts
- 12 oz penne pasta
- 1 tablespoon Cajun seasoning
- 4 cloves garlic
- 1 ½ cups heavy cream
- ½ cup chicken broth
- ½ cup shredded mozzarella cheese
- ½ cup shredded cheddar cheese
- ½ cup grated Parmesan cheese
- 2 tablespoons olive oil
- 3 tablespoons unsalted butter
- Salt and freshly ground black pepper, to taste
- Fresh parsley, chopped (for garnish)
Instructions
- Cook penne pasta according to package instructions until al dente. Drain and set aside.
- Season chicken with Cajun seasoning, salt, and pepper.
- In a large skillet over medium-high heat, heat olive oil and cook chicken until golden brown (about 6–8 minutes). Remove from skillet.
- In the same skillet, melt butter and sauté minced garlic for 1–2 minutes.
- Stir in heavy cream and chicken broth; simmer gently.
- Add mozzarella, cheddar, and Parmesan cheeses; stir until melted and smooth.
- Return chicken to the skillet; toss to coat with sauce.
- Mix in cooked penne pasta until fully combined.
- Garnish with chopped parsley before serving.
Nutrition
- Serving Size: 1 cup (250g)
- Calories: 620
- Sugar: 2g
- Sodium: 720mg
- Fat: 35g
- Saturated Fat: 20g
- Unsaturated Fat: 14g
- Trans Fat: 0g
- Carbohydrates: 50g
- Fiber: 3g
- Protein: 30g
- Cholesterol: 110mg